ACT — Nicotiana attenuata

Summary

A4A49_36170 (ACT, ARP2) in coyote tobacco (Nicotiana attenuata) encodes an actin-related protein 2 (ARP2) that contains an ATPase NBD domain and exhibits actin binding, profilin binding, phospholipid binding, and protein serine/threonine phosphatase activity. The gene is associated with actin cytoskeleton organization, actin nucleation, filament stabilization, cell tip growth, pronuclear migration, and Golgi-to-plasma membrane transport. It localizes to the actin cytoskeleton, Arp2/3 protein complex, cell cortex, and Golgi membrane. The gene has been linked to numerous agronomic traits including seed morphology, seed yield, leaf area, vegetative vigor, shoot branching, root hair length, water stress response, nitrogen and potassium sensitivity, aphid response, powdery mildew disease response, and osmotic stress tolerance. Related genes in other species are associated with pollen development, xylem development, root hair elongation, and pavement cell morphogenesis.