PNH — Nicotiana attenuata

Summary

A4A49_36480 (PNH, also known as AGO1B) in coyote tobacco (Nicotiana attenuata) encodes an Argonaute family protein containing Piwi, PAZ, and RNaseH-like domains, and is annotated with diverse molecular functions including siRNA binding, RNA endonuclease activity, and histone ubiquitin ligase activity. The gene is associated with miRNA and long siRNA processing, gene silencing by miRNA-directed mRNA cleavage, regulation of secondary metabolism, and temporal regulation of development. In this species, AGO7 has been linked to competitive growth. The gene is also associated with leaf polarity and morphology, auxin signalling, virus resistance, TAS3 ta-siRNA biogenesis, juvenile-to-adult transition, and traits including photosynthetic ability, root phototropism, UV light sensitivity, lignin biosynthesis, inflorescence development, seed dormancy, and leaf shattering. Related genes in other species are linked to histone ubiquitination, early flowering, pale leaves, and reduced seed dormancy.