ANS — Nicotiana attenuata

Summary

A4A49_36952 (ANS) in Nicotiana attenuata encodes a 2-oxoglutarate-dependent dioxygenase with jasmonic acid hydrolase activity, belonging to the IPNS-like Fe2OG oxygenase family. The gene is associated with the regulation of jasmonic acid-mediated signaling, anthocyanin and flavonoid biosynthesis, pigmentation, and secondary metabolism. It has been linked to flower color, anthocyanin and flavonoid content, and photosynthetic rate. The gene is also connected to biotic stress tolerance, including spider mite resistance and antifungal resistance, as well as drought stress tolerance and oxidative stress responses. Localized to the cytosol, it is associated with the downregulation of defense responses to insects and the regulation of anthocyanin and coumarin biosynthesis. Studies of related genes in other species link the family to jasmonic acid response and disease resistance.