HMG1 — Nicotiana attenuata
Summary
A4A49_37280 (HMG1) in coyote tobacco (Nicotiana attenuata) on chromosome 2 encodes a hydroxymethylglutaryl-CoA reductase (NADPH) (EC 1.1.1.34). The gene is associated with the mevalonate and MEP pathways, isoprenoid, sesquiterpenoid, triterpenoid, sterol, and salicylic acid anabolism, as well as protein prenylation, the MAPK cascade, induced systemic resistance, and regeneration. It is linked to photosynthetic rate, plant height, biomass, flowering time, male fertility, senescence, herbivore resistance, pathogen and wound responses, seed phytosterol content, cardenolide production, and light response. The encoded protein localizes to the endoplasmic reticulum, peroxisome, and chloroplast membranes. Studies of related genes in other species connect the family to mevalonate pathway regulation, isoprenoid biosynthesis, and phytosterol content.
Annotations
- Chromosome
- 2
- Related genes
- HMG1, HMG2
- GO terms
- Regeneration, Demethylation, Programmed Cell Death, Chloroplast Membrane, Seed Germination, terpenoid anabolism, Systemic Acquired Resistance, shoot development
- Publications
- 9245257, 20865301, 12198192, 11114204, 21601648, 26015445, 23572922, 20736450
- Traits
- mevalonate pathway regulation, isoprenoid biosynthesis, mevalonate synthesis, enzyme activity regulation, light response, Reduced Sterol and Triterpenoid Levels, Root Elongation Inhibition, Dwarf, Sterile, Rapid Leaf Senescence, plant development