HPL — Nicotiana attenuata

Summary

A4A49_36533 (HPL) in coyote tobacco (Nicotiana attenuata) encodes a cytochrome P450 family protein with allene oxide synthase, allene-oxide cyclase, hydro-lyase, lyase, monooxygenase and oxidoreductase activities, and binds iron and heme. It is associated with oxylipin and jasmonic acid biosynthesis, fatty acid metabolism, jasmonic acid signaling, the response to wounding, and defense responses. The gene product localises to chloroplast membranes, including the outer, inner, thylakoid and envelope membranes. HPL is associated with C6 volatile production, green leaf volatile biosynthesis and emission, hexenal signaling, aphid defense and herbivore resistance, as well as susceptibility to Pseudomonas syringae and arabidopside accumulation. Studies of related genes in other species link the family to indirect defense responses, aromatic volatile production, aphid resistance, insect resistance, fruit flavor and aroma, and traits such as linoleic acid content, plant height and root morphology.