SHD — Nicotiana attenuata

Summary

A4A49_36046, symbol SHD (NaSHD) in Nicotiana attenuata, encodes an ATP-dependent protein folding chaperone belonging to the heat shock protein 90 (HSP90) family, containing Hsp90_N, Hsp90_C, and HATPase_C domains. The gene is associated with protein folding, stabilization, and cellular response to heat, as well as defense response, cell death, secretion, viral translation, oviposition, NO storage, and homeostasis. Its product localizes to the cytoplasm, cytosol, ER lumen, perinuclear region, and plasmalemma. Studies of related genes in other species link the family to chaperone activity and stress responses, but these associations are not yet established for NaSHD itself.