COP1 — Nicotiana attenuata

Summary

A4A49_35805 (COP1) on chromosome 6 of coyote tobacco (Nicotiana attenuata) encodes a protein with a RING-type zinc finger and WD40 repeats, characteristic of the COP1 family, and possesses ubiquitin ligase activity, transcription corepressor binding, histone binding, and structural molecule activity. The gene is associated with photomorphogenesis, red/far-red light phototransduction, photoprotection, regulation of seed maturation, nicotine anabolism, nuclear export, protein ubiquitination, proteasomal pathway, chromatin modeling, DNA recombination and replication, and various intracellular transport processes including ER-to-Golgi and intra-Golgi transport. It localises to the nucleus, cytoplasm, Golgi membrane, coatomer, chromatin silencing complex, and DP/Rb/MuvB complex. Associations with chlorophyll content and plant height have also been noted. Related genes in other species link the family to chromatin regulation.