ERF1 — Nicotiana attenuata

Summary

A4A49_35180 (ERF1, also known as ERF1B) in coyote tobacco (Nicotiana attenuata) encodes an AP2/ERF domain-containing protein with DNA-binding and transcription coactivator activity. This gene is associated with the regulation of ethylene-mediated signaling, defense responses, and phytoalexin and nicotine biosynthesis. It is linked to trichome branching and papilla formation, as well as responses to drought, salinity, and red/far-red light. ERF1 is also associated with flower development regulation and phenylpropanoid metabolism. The encoded protein localizes to the nucleus and the mediator complex. Associations with traits such as disease tolerance, ethylene and auxin sensitivity, photosynthetic rate, heterosis, hydrogen peroxide content, and root and floral organ development have been reported. Related genes in other species are linked to resistance against Botrytis cinerea, necrotrophic pathogens, and various abiotic stresses.