HSP70 — Nicotiana attenuata

Summary

A4A49_26556 (HSP70) in coyote tobacco (Nicotiana attenuata) encodes a heat shock 70 family protein with ATP hydrolase activity, ATP binding, heat shock protein binding, and protein folding chaperone functions. It is associated with diverse biological processes including response to stress, heat, virus, and defense, as well as protein folding in the endoplasmic reticulum, the ERAD pathway, the unfolded protein response, calcium signaling, viral translation, virus-induced post-transcriptional gene silencing, leaf senescence, cell division, signal transduction, and phytochelatin anabolism. The gene product localizes to the cytoplasm, nucleus, membrane, tonoplast, chloroplast membrane, ER lumen, ER chaperone complex, and axonemal central pair projection. Associations with seed weight, seed size, lignin content, stomatal resistance, and chlorophyll content have been noted. Related genes in other species link this gene family to endoplasmic reticulum stress responses and protein quality control.