AGR — Nicotiana attenuata

Summary

A4A49_27140 (AGR, PIN2) in coyote tobacco (Nicotiana attenuata) encodes an auxin efflux carrier, a member of the Auxin Efflux Carrier family. The product possesses auxin efflux transmembrane transporter activity, as well as inositol-1,4-bisphosphate 1-phosphatase activity, 3'(2'),5'-bisphosphate nucleotidase activity, and binds various phosphatidylinositol phosphates and clathrin. This gene is associated with tropism, gravity response, phototropism, and response to oxidative stress. It is linked to traits including gravity response, blue light sensitivity, root and shoot growth angles, seed set percent, leaf vein morphology, and auxin content. Associations also extend to phenotypes such as primary root growth, root hair development, shoot apical dominance, lateral root organogenesis, and wound response. The gene product localizes to the auxin efflux carrier complex, basal and lateral plasma membranes, and recycling endosomes.