F3H — Nicotiana attenuata

Summary

A4A49_27372 (F3H) in coyote tobacco (Nicotiana attenuata) encodes a 2-oxoglutarate-dependent dioxygenase with flavanone 3-dioxygenase, flavone synthase, flavonol synthase and chalcone isomerase activities. The gene is associated with the regulation of flavonoid and anthocyanin biosynthesis, pigmentation, phenylpropanoid metabolism, coumarin anabolism, and responses to UV-B, fungal molecules and auxin. It has been linked to flower color, stamen morphology, root hair length, seed maturation, drought tolerance, oxidative stress response, and anthocyanin and flavonoid content. Phenotypic associations include powdery mildew resistance, pollen thermotolerance, cold acclimation, and proanthocyanidin accumulation. The protein localises to the tonoplast, endoplasmic reticulum, cytosol and nucleus.