LPP1 — Nicotiana attenuata

Summary

A4A49_27122 (LPP1/LPP4) in coyote tobacco (Nicotiana attenuata) encodes a protein with phosphatidate phosphatase and acid phosphatase activities, belonging to the PAP2/haloperoxidase superfamily. This gene is associated with phospholipid dephosphorylation, flavonoid and anthocyanin metabolism, phenylpropanoid metabolism, alkaloid anabolism, and secondary metabolism. It is linked to viral spread within multicellular hosts, plasmodesma-mediated cell-to-cell transport, detoxification, response to virus, response to UV-B, cellular response to hypoxia, ABA signaling, and leaf development. The encoded protein localizes to the plant-type cell wall, plasmodesmata, extracellular region, membrane, plasmalemma, and cytoplasm. Associations with photosynthetic rate, chlorophyll content, disease tolerance, seed dormancy, bolting time, seed yield, plant growth, flowering time, carbon metabolism, and energy-related traits have been noted. Studies of related genes in other species link the family to phosphorus utilization, tuber development, ABA sensitivity, pathogen susceptibility, and anthocyanin accumulation.