ROS1 — Nicotiana attenuata

Summary

A4A49_18220 (ROS1) in coyote tobacco (Nicotiana attenuata) on scaffold01940 encodes a DNA glycosylase with cytosine C-5 DNA demethylase and lyase activities, binding 4Fe-4S clusters and DNA. The product belongs to the DME/ROS1 family and localises to the nucleus. ROS1 is associated with chromosomal 5-methylcytosine DNA demethylation via the direct excision pathway, base excision repair, epigenetic regulation of gene expression, pigment accumulation, and anthocyanin biosynthesis. The gene has also been linked to drought tolerance. Studies of related genes in other species connect the ROS1 family to flavonoid content, anthocyanin content, chlorophyll content, plant height, and salt tolerance.