MLO — Nicotiana attenuata

Summary

A4A49_17889, designated MLO8 in coyote tobacco (Nicotiana attenuata) on scaffold00477, encodes a calmodulin-binding protein that also associates with protein binding. This gene is associated with the regulation of secondary metabolite biosynthesis, including nicotine and alkaloid anabolism, as well as salicylic acid anabolism and the metabolic burst. It is associated with pollen tube reception and guidance, auxin transport, response to hormone and stress, regulation of growth, RNA breakdown, protein processing, protein localization to the plasma membrane, NO storage, and homeostasis. The encoded protein localizes to the endomembrane system, membrane, mitochondria, plasmalemma, cytoplasm, and nucleus. Associations with shoot dry weight and drought tolerance have been recorded. Studies of related MLO family members in other species link the family to powdery mildew resistance and pollen tube guidance defects.