ERF1 — Nicotiana attenuata

Summary

A4A49_17723 (ERF1) in Nicotiana attenuata encodes an AP2/ERF domain-containing transcription factor that localizes to the nucleus and binds DNA in a sequence-specific manner. The gene is associated with the regulation of defense responses, ethylene-mediated signaling, and ethylene and nicotine biosynthesis. It has also been linked to fruit ripening, seed germination, autotrophy, viral genome replication, and virus-induced post-transcriptional gene silencing. Associations with traits include hydrogen peroxide content, heterosis, ethylene sensitivity, photosynthetic rate, and salt tolerance. The gene is connected to nematode resistance, phenolics accumulation, and defense against insect herbivory. Studies of related genes in other species link the family to abscisic acid sensitivity, cadmium tolerance, heat stress tolerance, bacterial leaf spot resistance, and fruit traits such as length, firmness, color, and weight.