DFR — Nicotiana attenuata

Summary

A4A49_17203 (DFR, also known as NaCCR4 or CCR4) on chromosome 6 of coyote tobacco (Nicotiana attenuata) encodes a protein with NAD(P)-binding and epimerase/dehydratase domains that exhibits dihydroflavanol 4-reductase, flavanone 4-reductase and cinnamyl-alcohol dehydrogenase activities (EC 1.1.1.234, 1.1.1.219). The gene is associated with anthocyanin, proanthocyanidin, flavonoid and lignin biosynthesis, as well as flavonol metabolism, pigmentation, leaf development, histogenesis, autotrophy, oxidative phosphorylation, secondary metabolism and virus-induced PTGS. It has been linked to flower color, anthocyanin content, photosynthetic rate and drought tolerance. Studies of related genes in other species connect the family to additional traits including leaf thickness, shoot biomass, fruit color, carotenoid and starch content, water use efficiency, stomatal resistance and chlorophyll content.