gh61-3 — Neurospora crassa

Summary

NCU02916 (gh61-3) on Neurospora crassa chromosome 1 encodes a protein of the AA9 family with cellulose-binding and copper-binding domains. The protein is annotated as an oxidoreductase (EC 1.14.99.56) with monooxygenase activity, oxygen binding, and cellulose binding, and is associated with cellulose breakdown, polysaccharide breakdown, and electron transfer. The encoded protein is localised extracellularly. Related genes in other species, such as AA9A and LPMO9H, link the family to oxidative cleavage of cellulose, though this specific activity is not established for gh61-3 itself. The gene is also associated with Verticillium dahliae through sequence similarity.