frq — Neurospora crassa

Summary

NCU02265, the frq gene on Neurospora crassa chromosome 7, encodes the FRQ protein, which possesses phase separation nucleator activity and protein homodimerization activity. This gene is associated with temperature compensation of the circadian clock, circadian rhythm, rhythmic behavior, and circadian behavior. It is also linked to blue light response, phototransduction, and bioluminescence. Beyond clock functions, frq is associated with pigmentation, asexual sporulation, regulation of phosphorylation, response to amino acid starvation, nuclear transport, cellular localization, and membraneless organelle assembly. The protein localizes to both the cytoplasm and nucleus.