cdt-1 — Neurospora crassa

Summary

NCU00801 (cdt-1) on Neurospora crassa chromosome 1 encodes a high-affinity glucose:proton symporter belonging to the major facilitator superfamily (MFS) of sugar transporters. The gene product is associated with cellobiose transport, glucose import, the glucose effect, and carbohydrate transport, as well as broader processes including cellulose breakdown, fermentation, secretion, endocytosis, and monocarboxylic acid metabolism. It is localized to the plasma membrane, particularly at the cell tip. Studies of related MFS sugar transporters in other species link the family to lactose permease activity, though this has not been established for cdt-1 itself.