chlE — Neurospora crassa

Summary

NCU00761 (symbol chlE) on Neurospora crassa chromosome 1 encodes a carboxylesterase belonging to the type-B carboxylesterase/lipase family, with chlorogenate hydrolase, carboxylesterase, and triacylglycerol lipase activities (EC 3.1.1.-). The gene is associated with (M)-viriditoxin anabolism, iron transport, lipolysis, and lipid metabolism, and its product localises to the extracellular space. Studies of related genes in other species link the family to carboxylesterase activities (EC 3.1.1.1, 3.1.1.3, 3.1.1.42) and to unaffected pathogenicity, though these associations are not established for N. crassa itself.