EXO70 — Magnaporthe oryzae 70-15

Summary

MoEXO70 (MGG_01760) on chromosome 2 of Magnaporthe oryzae 70-15 encodes an Exo70 family protein containing an Exo70_C domain and a cullin-repeat-like domain superfamily. The product binds phosphatidylinositol 4,5-bisphosphate and small GTPases, and is a core component of the exocyst complex localised at the plasma membrane, cellular bud tip, bud neck and incipient bud site. MoEXO70 is associated with exocyst assembly and localisation, exocytosis, Golgi-to-plasma-membrane transport, membrane fusion, protein transport, signal transduction, Rho protein signalling, polar cell growth, cell growth, appressorium formation, penetration peg formation, sucrose metabolism and ribosome biogenesis. The gene is also linked to abnormal endoplasmic reticulum and Golgi distribution, vesicle distribution, chitin deposition, spore wall formation, septum formation, budding, shmoo formation, filamentous growth, cell fusion, mating projection morphology, decreased necrotic cell death, increased thermotolerance and mating efficiency, and altered cell cycle progression.