SHD — Lactuca sativa

Summary

LsSHD, also known as LsHSP90, is a garden lettuce gene on chromosome 4 that encodes a heat shock protein 90 family chaperone with ATP-dependent protein folding activity. It is associated with numerous biological processes including cellular thermotolerance, response to unfolded protein, inhibition of heat stress response, brassinosteroid signaling, circadian clock photoentrainment, and defense responses involving respiratory burst. The gene has been linked to traits such as floral organ morphology, seed set, reproductive timing, photoperiod-sensitive flowering, temperature stress response, bacterial and viral disease responses, aphid response, submergence tolerance, and gibberellin-related traits. Localization evidence connects the product to the chloroplast outer membrane, ER lumen, plasma membrane, and vesicle compartments. Studies of related HSP90 family members in other species link the family to thermotolerance, broad-spectrum disease resistance, salinity tolerance, and developmental regulation.