BET9 — Lactuca sativa

Summary

LsBET9, encoded by the garden lettuce gene LSAT_V11C400167910 on chromosome 4, is a bromodomain-containing protein with histone acetylase activity, histone binding, SUMO transferase activity, and DNA-binding transcription factor activity. It is associated with the regulation of nitrate assimilation, salicylic acid metabolism, systemic acquired resistance, antiviral responses, and chromatin reassembly. The gene has been linked to numerous agronomically relevant traits including seed protein content, seed dormancy, flowering time, whole plant size, root morphology, anthocyanin content, and responses to high and low temperature stress, oxidative stress, aluminum, copper, nitrate, phosphorus, and auxin. It is also associated with disease tolerance, Botrytis cinerea resistance, and nitrogen use efficiency. Studies of related genes in other species link the family to cell cycle regulation, immune response, and ploidy level.