GA5 — Lactuca sativa

Summary

LsGA5 (GA5, GA20OX1) on chromosome 4 of garden lettuce encodes a gibberellin 20-oxidase, a 2-oxoglutarate-dependent dioxygenase that also exhibits flavanone 3-dioxygenase activity and binds metal ions and vitamin C. The gene is associated with gibberellin signaling and biosynthesis, and with responses to flooding, red or far red light, light stimulus, and oomycete defense. It is linked to the regulation of growth, leaf and flower development, polar cell growth, and flavonoid anabolism. Associations with plant height, stem height, leaf size, biomass, flowering time, seed germination, fruit set, parthenocarpy, root growth, salt stress tolerance, wind tolerance, ethylene sensitivity, and adaptation to high altitude have been reported. The product localizes to the cytoplasm. Studies of related genes in other species connect the family to stem and internode elongation, fruit development, trichome formation, and salt tolerance.