LOX — Lactuca sativa

Summary

LsLOX, on chromosome 4 of garden lettuce (Lactuca sativa), encodes a lipoxygenase enzyme with linoleate 9S- and 13S-lipoxygenase activities, phytoene dehydrogenase activity, and peroxidase activity. It is associated with oxylipin and jasmonic acid biosynthesis, green leaf volatile production, and responses to herbivores, insects, ozone, and high light intensity. The gene is linked to traits including nitrate content, photoperiod-sensitive flowering, seed yield, photosynthetic rate, root thickness, and low temperature stress response. It is associated with wound response, jasmonate accumulation, drought resistance, cadmium stress tolerance, and defense against herbivory. Localisation evidence places the product in chloroplast thylakoids, the chloroplast envelope, apoplast, and stress granules. Studies of related genes in other species link the family to resistance to fungal pathogens, herbivory, and potyviruses, as well as leaf senescence and stomatal closure.