WR3 — Lactuca sativa

Summary

LsWR3 (WR3, NRT3.1, NRT3.2, LsNAR2) on chromosome 4 of garden lettuce (Lactuca sativa) encodes a protein with nitrate transmembrane transporter activity. The gene is associated with nitrate transmembrane transport, cellular response to nitrate, response to wounding, and cell wall organization, and its product localizes to the membrane, plasmalemma, and cytoplasm. LsWR3 is associated with nitrogen sensitivity, nitrate sensitivity, biomass yield, seed yield, root hair length, root development, flowering time, anthocyanin content, drought tolerance, and disease tolerance. It is also linked to impaired nitrate uptake, lateral root development, cadmium accumulation, pathogen resistance, and nitrogen remobilization. Studies of related genes in other species, including Arabidopsis NRT3.1, link the family to high-affinity nitrate uptake and nitrate accumulation.