FL1 — Lactuca sativa

Summary

LsFL1, located on chromosome 4 of garden lettuce (Lactuca sativa), encodes a protein with a K-box domain and is annotated with sequence-specific DNA binding, transcription coactivator activity, and protein dimerization activities. The gene is associated with the regulation of flowering time, particularly through photoperiodism and vernalization response, as well as floral meristem identity and floral whorl development. It has been linked to traits including days to flowering, flower and inflorescence morphology, seed protein content, water use efficiency, leaf size and chlorosis, anthocyanin content, and responses to abiotic stresses such as high temperature, aluminum, and copper. Localization evidence places the product in the nucleus, nucleolus, and plasmalemma. Studies of related genes in other species connect the family to flowering transition, vernalization sensitivity, and thermosensory flowering.