TS1 — Lactuca sativa

Summary

LsTS1 (TS1), located on chromosome 2 of garden lettuce (Lactuca sativa), encodes a terpene synthase with multiple annotated activities, including germacrene-A synthase, alpha-copaene synthase, (+)-delta-cadinene synthase, alpha-humulene synthase, and sesquiterpene synthase activity. The protein contains terpene synthase and cyclase domains, binds magnesium, and has redox activity. It is associated with farnesyl diphosphate metabolism, terpenoid metabolism, diterpenoid anabolism, sesquiterpene biosynthesis, and terpene anabolism, and is localized to the cytoplasm. Studies of related genes in other species link the family to additional sesquiterpene synthase activities, including EC 4.2.3.173 and 4.2.3.172, though these associations are not yet established in lettuce.