M2 — Lactuca sativa

Summary

LsM2, the gene symbol for LSAT_V11C200070230 on garden lettuce chromosome 2, encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (PPIase) with cis-trans proline isomerase activity and cyclosporin A binding capability. This gene is associated with protein folding, regulation of protein refolding, and responses to abscisic acid, salt, and mannitol. It is associated with sesquiterpenoid metabolism, lactone anabolism, sporopollenin biosynthesis, and activation of the salinity response. The encoded product localises to the chloroplast stroma, cytosol, plasma membrane, cytoplasm, and nucleus. Related genes in other species link the cyclophilin family to heterosis.