DFR — Lactuca sativa

Summary

LsDFR (DFR, TT3) on chromosome 2 of garden lettuce encodes a protein with epimerase_deHydtase and NAD(P)-bd_dom_sf domains and exhibits flavanone 4-reductase, dihydroflavanol 4-reductase, chalcone isomerase, naringenin-chalcone synthase, flavonol synthase and protein-binding activities. The gene is associated with anthocyanin, flavonoid, chalcone and flavonol biosynthesis, pigment accumulation and pigmentation, as well as responses to UV, UV-B, jasmonic acid, wounding, light, gravity, oxidative stress and auxin polar transport. It is linked to leaf color, anthocyanin and flavonoid content, chlorophyll content, photosynthetic rate and quantum yield, shoot fresh and dry weight, leaf number, stamen morphology, flower development, root phototropism, adventitious rootless, herbicide sensitivity, insect damage, low temperature and oxidative stress tolerance, stomatal resistance and closure time. Related genes in other species are linked to proanthocyanidin biosynthesis, seed coat pigmentation, UV-B sensitivity, oxidative stress tolerance and genome stability.