HPD — Lactuca sativa

Summary

LsHPD (LSAT_V11C200085720) on lettuce chromosome 2 encodes a 4-hydroxyphenylpyruvate dioxygenase, an enzyme with 4-hydroxyphenylpyruvate dioxygenase activity, iron binding, metal binding, and identical protein binding. This gene is associated with vitamin B6 anabolism, plastoquinone anabolism, tyrosine breakdown, vitamin A anabolism, L-phenylalanine breakdown, vitamin E anabolism, carotenoid anabolism, and seed germination. It has been linked to chlorophyll content and to plastoquinone, tocopherol, and carotenoid synthesis. The encoded protein is predicted to localise to the cytosol, mitochondria, and extracellular space. Studies of related genes in other species connect the HPD family to herbicide sensitivity, leaf necrosis, seed weight, plant height, and responses to high light stress and parasitic weeds, as well as to photosynthesis and vitamin E content.