MS1 — Lactuca sativa

Summary

LsMS1, on lettuce chromosome 2, encodes a cobalamin-independent methionine synthase, also annotated with ADP-glucose pyrophosphatase, ADP-ribose pyrophosphatase, and nucleoside diphosphatase activities, as well as DNA-binding transcription factor activity. The gene is associated with de novo L-methionine biosynthesis, regulation of starch biosynthesis, DNA methylation-dependent heterochromatin assembly, and responses to ozone, oxidative stress, bacteria, insects, and hypoxia. It is linked to traits including whole plant size, seed growth and development, root morphology, disease tolerance, and oxidative stress response. Associations with male sterility, pollen exine development, anther development, and chromatin silencing are also recorded. Related genes in other species are linked to seed germination, salt tolerance, immunity, pathogen defense, callose deposition, and indolic glucosinolate biosynthesis.