HPD — Lactuca sativa

Summary

LsHPD (LSAT_V11C200085730) on chromosome 2 of garden lettuce encodes a 4-hydroxyphenylpyruvate dioxygenase, an iron-binding enzyme of the VOC superfamily. The gene is associated with the biosynthesis of plastoquinone, carotenoids, tocopherols, and vitamins A, B6, and E, as well as with tyrosine and L-phenylalanine catabolism and seed germination. It has been linked to chlorophyll content and to plastoquinone, tocopherol, and carotenoid synthesis. The encoded protein is predicted to localise to the cytosol, mitochondria, and extracellular space. Studies of related genes in other species connect the family to herbicide sensitivity, leaf necrosis, seed weight, plant height, and responses to high light stress and parasitic weeds.