CHS — Lactuca sativa

Summary

LsCHS, encoded by the gene LSAT_V11C200065530 on chromosome 2 of garden lettuce (Lactuca sativa), is a member of the chalcone/stilbene synthase and polyketide synthase type-III families. The gene product exhibits naringenin-chalcone synthase, chalcone isomerase, flavanone 4-reductase, dihydroflavanol 4-reductase, flavonol synthase, and tetraketide alpha-pyrone synthase activities, and is associated with chalcone, flavonoid, anthocyanin, and polyketide biosynthesis. It has been linked to responses to UV-B light, jasmonic acid, oxidative stress, gravity, and heat acclimation, as well as auxin polar transport and sumoylation. Associations with traits include anthocyanin content, chlorophyll content, photosynthetic and respiration rates, shoot fresh weight, flowering time, root morphology, and tolerance to salt, drought, and nitrogen stress. The gene is also associated with pollen exine development, male sterility, and pathogen response.