CHS — Lactuca sativa

Summary

LsCHS, on chromosome 2 of garden lettuce, encodes a chalcone/stilbene synthase family protein with polyketide synthase type-III domains and multiple annotated enzyme activities including naringenin-chalcone synthase, chalcone isomerase, and flavonol synthase activities. The gene is associated with chalcone, flavonoid, anthocyanin, and polyketide biosynthesis, as well as responses to UV light, jasmonic acid, gravity, and heat acclimation. It is linked to traits including anthocyanin content, chlorophyll content, photosynthetic rate, shoot fresh weight, flowering time, root morphology, and abiotic stress responses including salt and drought tolerance. Associations also include pollen exine development, male sterility, root-knot nematode resistance, and pathogen response. Studies of related genes in other species link the family to seed coat pigmentation, flavonol biosynthesis, and UV-B sensitivity.