BET9 — Lactuca sativa

Summary

LsBET9, encoded by the garden lettuce gene LSAT_V11C100012090 on chromosome 1, is a bromodomain-containing protein with DNA-binding, transcription coactivator, histone-binding, SUMO-binding, calmodulin-binding, and tRNA-adenosine deaminase activities. It is associated with the positive regulation of the mitotic cell cycle, viral processes, telomere maintenance, nitrate assimilation, tRNA wobble adenosine-to-inosine editing, and the regulation of salicylic acid metabolism and abscisic acid-mediated signalling. The gene has been linked to traits including seed protein content, whole plant size, root hair length, lateral root length, anthocyanin content, flowering time, disease tolerance, and responses to copper, nitrate, aluminum, auxin, high and low temperature, oxidative stress, and salinity. It is also associated with phenotypes such as resistance to Botrytis cinerea, drought tolerance, and nitrogen use efficiency.