CYP — Lactuca sativa

Summary

LsCYP95 (gene symbol CYP, chromosome 1) encodes a cyclophilin-type peptidylprolyl isomerase (PPIase) with cis-trans proline isomerase activity, RNA folding chaperone function, and cyclosporin A binding. It is associated with protein folding, regulation of protein refolding, RNA splicing, and mRNA splicing via the spliceosome. The gene is linked to sesquiterpenoid metabolism, lactone anabolism, sporopollenin biosynthesis, and responses to abscisic acid, cold, salt, and mannitol. It is associated with cold acclimation, activation of salinity response, and polar cell growth. Localization evidence places the product in the nucleus, cytosol, cytoplasm, chloroplast stroma, mitochondria, plasmalemma, and nuclear speck. Associations with agronomic traits include leaf length, cell elongation, heterosis, and tolerance to drought, freezing, salt, and oxidative stress, as well as cell size, endoreplication, and organ growth. Related genes in other species link the family to drought and freezing tolerance.