LOX — Lactuca sativa

Summary

LsLOX, encoded by the gene LSAT_V11C100022210 on chromosome 1 of garden lettuce (Lactuca sativa), is a lipoxygenase family protein containing the characteristic LipOase, PLAT/LH2 and iron-binding domains. It possesses linoleate 13S-lipoxygenase and phytoene dehydrogenase activities, acting as an oxidoreductase that incorporates molecular oxygen. The gene is associated with the biosynthesis of green leaf volatiles and oxylipins, as well as fatty acid and terpenoid anabolism. It has been linked to responses to wounding, jasmonic acid, salicylate and other organisms, and to lipid oxidation, triglyceride metabolism and translation elongation. The product localises to the chloroplast thylakoid and stroma. Studies of related genes in other species connect the family to linoleate 13S-lipoxygenase activity (EC 1.13.11.12). The gene is also associated with nitrate content and nitrate transport.