HY3 (LSAT_V11C100017430) — Lactuca sativa

Summary

LsHY3, encoded by the gene LSAT_V11C100017430 on chromosome 1 of garden lettuce (Lactuca sativa), is a member of the phytochrome A-E family, containing domains such as PAS, GAF, and a histidine kinase domain. The gene is associated with tetrapyrrole binding and a wide array of molecular functions, including transcription regulator activator activity and adenylyltransferase activity. It has been linked to biological processes such as detection of light, regulation of response to red or far red light, positive regulation of the phytochrome signaling pathway, and protein-phycocyanobilin linkage. Associations with agronomically relevant traits include light quality response, photoperiod sensitivity, chlorophyll ratio, grain yield, leaf area, plant dry weight, and vegetative vigor. The gene is also connected to phenotypes such as delayed flowering, drought stress response, cold stress response, disease resistance, and anthocyanin synthesis. Studies of related genes in other species link the phytochrome family to traits including fruit ripening, tuberization, and salinity tolerance.