PNH — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.4HG0334500, designated HvPNH on barley chromosome 4H, encodes a member of the Argonaute protein family, containing Piwi, PAZ and RNaseH-like domains. The product is associated with diverse molecular functions including siRNA and miRNA binding, histone ubiquitin ligase and deubiquitinase activities, and DNA-binding transcription activator activity. HvPNH is linked to miRNA and tasiRNA metabolic processes, gene silencing by miRNA, somatic stem cell population maintenance, regulation of cell fate specification, and female meiotic nuclear division. It has been connected to agronomically relevant traits such as spikelet fertility, spikelet number, photosynthetic ability, inflorescence development, leaf morphology, root phototropism, and responses to UV light, osmotic stress, and metal stress. Studies of related genes in other species link the family to meiosis, antiviral immunity, shoot apical meristem initiation, and grain yield.