LOX1 — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.4HG0335800, designated LOX1 (synonyms LoxB, HvLOX1, HvLOX5, LOX5, and others) on barley chromosome 4H, encodes a lipoxygenase with linoleate 9S-lipoxygenase and linoleate 13S-lipoxygenase activities, containing LipOase and PLAT/LH2 domains. The gene is associated with jasmonic acid and oxylipin biosynthesis, lipid oxidation, membrane breakdown, and responses to wounding, abscisic acid, jasmonic acid, and other organisms. It has been linked to grain dormancy, photosynthetic rate, and numerous stress and defence phenotypes including resistance to Fusarium head blight, aphids, and pathogens, as well as tolerance to drought, heat, oxidative stress, and cadmium. The product localises to plastids and cytoplasm and is associated with root development and lateral root formation. Studies of related lipoxygenases in other species associate the family with seed longevity, leaf senescence, and insect resistance.