PAP5 — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.4HG0336140 (symbol HvPAP5, also known as HvSAG12) on barley chromosome 4H encodes a papain-like cysteine peptidase belonging to the peptidase C1A family, with thiol endopeptidase activity and proteinase-activated receptor binding. The gene is associated with leaf senescence, programmed cell death, cell death, proteolysis, protein breakdown, responses to abscisic acid, ethylene, and gibberellin, and the MVA and MEP pathways. The encoded protein localises to the senescence-associated vacuole, lysosome, protein storage vacuole, aleurone body, and ER lumen. Related genes in other species, such as rice SAG39 and EP3A, link the family to similar senescence and proteolytic processes.