tdiB — Aspergillus nidulans FGSC A4

Summary

ANIA_08514 (tdiB) on chromosome 5 of Aspergillus nidulans FGSC A4 encodes a prenyltransferase with transferase activity for alkyl or aryl groups (EC 2.5.1.-) and metal binding, belonging to the aromatic prenyltransferase DMATS family. The gene is associated with prenylation, secondary metabolism, and the biosynthesis of alkaloids, alcohols, isoprenoids, mycotoxins, sterigmatocystin, and terrequinone A. It is linked to the related gene terF. Studies of related genes in other species, including Fusarium oxysporum strains and homologs such as ltmE, amyD, idtF, ltmF, and PaPT, connect these aromatic prenyltransferases to secondary metabolite production, though these associations are not established for tdiB itself.