GL3 — Arabidopsis thaliana

Summary

AT5G41315 (GL3, GLABROUS 3) in Arabidopsis thaliana encodes a MYC6.2 protein with a bHLH domain, possessing DNA binding, transcription coactivator activity, and protein dimerization activity. It is associated with epidermal cell fate specification, lateral inhibition, and regulation of trichome spacing and morphogenesis. The gene is linked to root hair development, endoreduplication, and trichome clustering and density. GL3 has been connected to numerous traits including leaf trichome density, seed color, root epidermal cell length, stem length, leaf lamina area, cadmium concentration, iron concentration, and plant male sterility. It localizes to the nucleus, cytoplasm, and plasmalemma, and is associated with jasmonic acid signaling and hormone signaling pathways. Related genes in other species are linked to anthocyanin production, root hair patterning, and stomatal formation.