PT1 — Arabidopsis thaliana

Summary

AT5G43350 (PT1, AtPT1, PHT1;1) encodes a major facilitator superfamily (MFS) domain-containing protein with phosphate transmembrane transporter, arsenate ion transmembrane transporter, and symporter activities. This thale-cress gene on chromosome 5 is associated with phosphorus acquisition, uptake, and homeostasis, as well as phosphate starvation responses and cellular responses to phosphate starvation. It has been connected to arsenic accumulation, arsenate tolerance and sensitivity, selenium uptake and tolerance, and lead and chromium responses. The gene is linked to root hair density, root branching, root length, lateral root development, leaf chlorosis, anthocyanin content, drought tolerance, temperature stress tolerance, and organ growth. It is associated with membrane transport, endocytosis, auxin transport, calcium signaling, acid secretion, and nitrate import. The protein localizes to the plasma membrane, vacuole, Golgi complex, plasmodesma, and cytoplasm. Related genes in other species are associated with phosphate transport.