FLS2 — Arabidopsis thaliana

Summary

AT5G46330 (FLS2) in Arabidopsis thaliana encodes a leucine-rich repeat receptor-like kinase (LRR-RLK) with transmembrane receptor serine/threonine kinase activity. FLS2 is associated with immunity, flagellin perception, and pathogen-associated molecular pattern-triggered immunity, as well as antibacterial resistance and induced systemic resistance. It is linked to leaf wilting, rhizosphere microbiome composition, and flg22-induced resistance to Fusarium graminearum. The gene is also connected to diverse traits including spikelet fertility, leaf rolling response, hybrid incompatibility, bacterial blight disease resistance, and biomass yield. FLS2 is associated with signaling, calcium ion homeostasis, and responses to biotic stimuli. Studies of related genes in other species link the family to susceptibility to Pseudomonas pathogens and heterochromatin condensation.