PBS2 — Arabidopsis thaliana

Summary

AT5G51700 (PBS2, also known as AtRAR1) encodes a CHORD domain-containing protein RAR1 that binds Hsp90, chaperone proteins, and proteases, and exhibits ATP hydrolase and metal-binding activities. In Arabidopsis, RAR1 is associated with disease resistance, basal defense, hypersensitive cell death, and Agrobacterium-mediated transformation. It is linked to defense responses against other organisms, regulation of the hypersensitive response, respiratory burst involved in defense, and response to auxin stimulus. The protein localizes to the SCF complex, stress granules, chloroplast envelope, and other cellular compartments. RAR1 is also associated with traits including root morphology, leaf senescence, flowering time, temperature stress response, disease tolerance, and auxin sensitivity. Studies of related genes in other species link the RAR1 family to bacterial and Fusarium disease resistance.