AGR — Arabidopsis thaliana

Summary

AT5G57090, also known as AGR, PIN2, EIR1, and WAV6 in Arabidopsis thaliana, encodes an auxin efflux carrier protein belonging to the Auxin Efflux Carrier family. The gene product exhibits auxin efflux transmembrane transporter activity, inositol-1,4-bisphosphate 1-phosphatase activity, and binds various phosphatidylinositol phosphates and clathrin. AGR is associated with a wide range of biological processes including axis elongation, lateral root branching, halotropism, sleep, and response to oxidative stress. It localizes to the basal plasma membrane, recycling endosome, and clathrin-coated vesicles. The gene is linked to numerous traits such as root system depth, gravity response, biomass yield, carbon isotope discrimination, leaf relative water content, seed set percent, shoot growth angle, and responses to aluminum, manganese, blue light, and temperature stress. Observed phenotypes include root growth direction, cell elongation, biomass production, and cotyledon vasculature formation.