SIZ1 — Arabidopsis thaliana

Summary

AT5G60410 (SIZ1) in Arabidopsis thaliana encodes an E3 SUMO-protein ligase with SUMO transferase activity. SIZ1 is associated with phosphate deficiency response, nitrogen assimilation, abiotic stress tolerance, pathogen defense, seed storage protein accumulation, chloroplast protein import, protein sumoylation, regulation of salicylic acid metabolism, thermomorphogenesis, and responses to high light and arsenite. Associations extend to traits such as phosphate and nitrate content, seed protein content, root hair density, leaf area index, inflorescence height, and resistance to the nematode Meloidogyne incognita. The gene product localizes to nuclear ubiquitin ligase complexes, chloroplast membranes, and the SCF complex. Studies of related genes in other species link the SIZ1 family to transposon silencing and virus tolerance.