E112 — Arabidopsis thaliana

Summary

AT5G64740 (IXR2, also known as CESA6) encodes a cellulose synthase (UDP-forming) enzyme. The gene is associated with primary cell wall biogenesis, regulation of cellulose anabolism, cellulose breakdown, regulation of microtubule dynamics, microtubule assembly, pollen tube cell wall formation, regulation of root morphogenesis, cell tip growth, seed coat mucilage development, and cell adhesion. Associations with traits include plant vigor, biomass yield, stem elongation, water use efficiency, seed protein content, oleic acid content, lignin content, and responses to salt stress, drought, and powdery mildew. The protein localizes to the plasma membrane, cortical microtubules, cell plate, and early endosomes. Studies of related genes in other species link the family to leaf and fruit size, seed coat morphology, and disease resistance.